Toxicology In Vitro

Journal Title：Toxicology In Vitro

Toxicology in Vitro publishes original research papers and reviews on the application and use of in vitro systems for assessing or predicting the toxic effects of chemicals and elucidating their mechanisms of action. These in vitro techniques include utilizing cell or tissue cultures, isolated cells, tissue slices, subcellular fractions, transgenic cell cultures, and cells from transgenic organisms, as well as in silico modelling. The Journal will focus on investigations that involve the development and validation of new in vitro methods, e.g. for prediction of toxic effects based on traditional and in silico modelling; on the use of methods in high-throughput toxicology and pharmacology; elucidation of mechanisms of toxic action; the application of genomics, transcriptomics and proteomics in toxicology, as well as on comparative studies that characterise the relationship between in vitro and in vivo findings. The Journal strongly encourages the submission of manuscripts that focus on the development of in vitro methods, their practical applications and regulatory use (e.g. in the areas of food components cosmetics, pharmaceuticals, pesticides, and industrial chemicals). Toxicology in Vitro discourages papers that record reporting on toxicological effects from materials, such as plant extracts or herbal medicines, that have not been chemically characterized.

Toxicology in Vitro 发表关于体外系统在评估或预测化学品毒性作用并阐明其作用机制方面的应用和使用的原创研究论文和评论。这些体外技术包括利用细胞或组织培养物、分离的细胞、组织切片、亚细胞部分、转基因细胞培养物和来自转基因生物的细胞，以及计算机建模。该杂志将重点关注涉及新体外方法的开发和验证的调查，例如用于基于传统和计算机模拟的毒性效应预测；关于高通量毒理学和药理学方法的使用；阐明毒性作用机制；基因组学、转录组学和蛋白质组学在毒理学中的应用，以及用于表征体外和体内发现之间关系的比较研究。该杂志强烈鼓励提交侧重于体外方法开发、实际应用和监管用途的手稿（例如在食品成分化妆品、药物、杀虫剂和工业化学品领域）。 Toxicology in Vitro 不鼓励那些记录有关未经化学表征的材料（例如植物提取物或草药）的毒理学影响的论文。

Toxicology In Vitro创刊于1987年，由PERGAMON-ELSEVIER SCIENCE LTD出版商出版，收稿方向涵盖医学 - 毒理学全领域，此刊是中等级别的SCI期刊，所以过审相对来讲不是特别难，但是该刊专业认可度不错，仍然是一本值得选择的SCI期刊 。平均审稿速度约2.0个月，影响因子指数2.959，该期刊近期没有被列入国际期刊预警名单，广大学者值得一试。